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Centering, scaling, and transformations: improving the biological information content of metabolomics data

BACKGROUND: Extracting relevant biological information from large data sets is a major challenge in functional genomics research. Different aspects of the data hamper their biological interpretation. For instance, 5000-fold differences in concentration for different metabolites are present in a meta...

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Detalles Bibliográficos
Autores principales: van den Berg, Robert A, Hoefsloot, Huub CJ, Westerhuis, Johan A, Smilde, Age K, van der Werf, Mariët J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534033/
https://www.ncbi.nlm.nih.gov/pubmed/16762068
http://dx.doi.org/10.1186/1471-2164-7-142