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A QTL on rat chromosome 7 modulates prepulse inhibition, a neuro-behavioral trait of ADHD, in a Lewis x SHR intercross

BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is a complex neuropsychiatric disorder with a substantial genetic component. The Spontaneously Hypertensive Rats (SHR), considered as a good animal model of ADHD, also show less anxiety-like behaviors than Lewis (LEW) rats. The use of these...

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Detalles Bibliográficos
Autores principales: Vendruscolo, Leandro Franco, Terenina-Rigaldie, Elena, Raba, Frantz, Ramos, André, Takahashi, Reinaldo Naoto, Mormède, Pierre
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534047/
https://www.ncbi.nlm.nih.gov/pubmed/16768795
http://dx.doi.org/10.1186/1744-9081-2-21