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Using ESTs to improve the accuracy of de novo gene prediction
BACKGROUND: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Gene prediction systems based exclusively on EST alignments miss these exons and genes, leading to poor sensitivity. De nov...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534067/ https://www.ncbi.nlm.nih.gov/pubmed/16817966 http://dx.doi.org/10.1186/1471-2105-7-327 |