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Predicting DNA-binding sites of proteins from amino acid sequence

BACKGROUND: Understanding the molecular details of protein-DNA interactions is critical for deciphering the mechanisms of gene regulation. We present a machine learning approach for the identification of amino acid residues involved in protein-DNA interactions. RESULTS: We start with a Naïve Bayes c...

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Detalles Bibliográficos
Autores principales: Yan, Changhui, Terribilini, Michael, Wu, Feihong, Jernigan, Robert L, Dobbs, Drena, Honavar, Vasant
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534068/
https://www.ncbi.nlm.nih.gov/pubmed/16712732
http://dx.doi.org/10.1186/1471-2105-7-262