Family-Based versus Unrelated Case-Control Designs for Genetic Associations

The most simple and commonly used approach for genetic associations is the case-control study design of unrelated people. This design is susceptible to population stratification. This problem is obviated in family-based studies, but it is usually difficult to accumulate large enough samples of well-...

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Detalles Bibliográficos
Autores principales: Evangelou, Evangelos, Trikalinos, Thomas A, Salanti, Georgia, Ioannidis, John P. A
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534078/
https://www.ncbi.nlm.nih.gov/pubmed/16895437
http://dx.doi.org/10.1371/journal.pgen.0020123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534078/
https://www.ncbi.nlm.nih.gov/pubmed/16895437
http://dx.doi.org/10.1371/journal.pgen.0020123

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