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Family-Based versus Unrelated Case-Control Designs for Genetic Associations
The most simple and commonly used approach for genetic associations is the case-control study design of unrelated people. This design is susceptible to population stratification. This problem is obviated in family-based studies, but it is usually difficult to accumulate large enough samples of well-...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534078/ https://www.ncbi.nlm.nih.gov/pubmed/16895437 http://dx.doi.org/10.1371/journal.pgen.0020123 |