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Statins stimulate arachidonic acid release and prostaglandin I(2 )production in rat liver cells

Statins inhibit 3-hydroxy-3-methylglutaryl (HMG-CoA) reductase, the rate limiting step in cholesterol synthesis. They are, therefore, used clinically to lower cholesterol and prevent atherosclerosis. Statins have beneficial effects on multiple organ systems. Some of these effects are found in the ab...

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Detalles Bibliográficos
Autor principal: Levine, Lawrence
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153527/
https://www.ncbi.nlm.nih.gov/pubmed/12689340
http://dx.doi.org/10.1186/1476-511X-2-1