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Statins stimulate arachidonic acid release and prostaglandin I(2 )production in rat liver cells
Statins inhibit 3-hydroxy-3-methylglutaryl (HMG-CoA) reductase, the rate limiting step in cholesterol synthesis. They are, therefore, used clinically to lower cholesterol and prevent atherosclerosis. Statins have beneficial effects on multiple organ systems. Some of these effects are found in the ab...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2003
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153527/ https://www.ncbi.nlm.nih.gov/pubmed/12689340 http://dx.doi.org/10.1186/1476-511X-2-1 |