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The use of a physiologically based pharmacokinetic model to evaluate deconvolution measurements of systemic absorption
BACKGROUND: An unknown input function can be determined by deconvolution using the systemic bolus input function (r) determined using an experimental input of duration ranging from a few seconds to many minutes. The quantitative relation between the duration of the input and the accuracy of r is unk...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2003
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC153531/ https://www.ncbi.nlm.nih.gov/pubmed/12659643 http://dx.doi.org/10.1186/1472-6904-3-1 |