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TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells

BACKGROUND: Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the mechanism of caspase-9 inhibition, with a fo...

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Detalles Bibliográficos
Autores principales: Checinska, Agnieszka, Giaccone, Giuseppe, Hoogeland, Bas SJ, Ferreira, Carlos G, Rodriguez, Jose A, Kruyt, Frank AE
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538619/
https://www.ncbi.nlm.nih.gov/pubmed/16796750
http://dx.doi.org/10.1186/1471-2407-6-166