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TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells
BACKGROUND: Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to chemotherapy shown in this type of tumor. The aim of the present study was to investigate the mechanism of caspase-9 inhibition, with a fo...
Autores principales: | Checinska, Agnieszka, Giaccone, Giuseppe, Hoogeland, Bas SJ, Ferreira, Carlos G, Rodriguez, Jose A, Kruyt, Frank AE |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538619/ https://www.ncbi.nlm.nih.gov/pubmed/16796750 http://dx.doi.org/10.1186/1471-2407-6-166 |
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