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ReadOut: structure-based calculation of direct and indirect readout energies and specificities for protein–DNA recognition
Protein–DNA interactions play a central role in regulatory processes at the genetic level. DNA-binding proteins recognize their targets by direct base–amino acid interactions and indirect conformational energy contribution from DNA deformations and elasticity. Knowledge-based approach based on the s...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538882/ https://www.ncbi.nlm.nih.gov/pubmed/16844974 http://dx.doi.org/10.1093/nar/gkl104 |