Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases

Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are specific for nearly any site in the genome. These domains can be treated as modular units and assembled to create a polydacty...

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Detalles Bibliográficos
Autores principales: Mandell, Jeffrey G., Barbas, Carlos F.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538883/
https://www.ncbi.nlm.nih.gov/pubmed/16845061
http://dx.doi.org/10.1093/nar/gkl209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538883/
https://www.ncbi.nlm.nih.gov/pubmed/16845061
http://dx.doi.org/10.1093/nar/gkl209

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