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The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion

BACKGROUND: Lipoprotein Lipase (LPL), a key enzyme in lipid metabolism, catalyzes the hydrolysis of triglycerides (TG) from TG-rich lipoproteins, and serves a bridging function that enhances the cellular uptake of lipoproteins. Abnormalities in LPL function are associated with pathophysiological con...

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Detalles Bibliográficos
Autores principales: Wung, Shu-Fen, Kulkarni, Medha V, Pullinger, Clive R, Malloy, Mary J, Kane, John P, Aouizerat, Bradley E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538992/
https://www.ncbi.nlm.nih.gov/pubmed/16822320
http://dx.doi.org/10.1186/1476-511X-5-19