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Can the state of cancer chemotherapy resistance be reverted by epigenetic therapy?
BACKGROUND: Transcriptome analysis shows that the chemotherapy innate resistance state of tumors is characterized by: poorly dividing tumor cells; an increased DNA repair; an increased drug efflux potential by ABC-transporters; and a dysfunctional ECM. Because chemotherapy resistance involves multip...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540437/ https://www.ncbi.nlm.nih.gov/pubmed/16831224 http://dx.doi.org/10.1186/1476-4598-5-27 |