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Can the state of cancer chemotherapy resistance be reverted by epigenetic therapy?

BACKGROUND: Transcriptome analysis shows that the chemotherapy innate resistance state of tumors is characterized by: poorly dividing tumor cells; an increased DNA repair; an increased drug efflux potential by ABC-transporters; and a dysfunctional ECM. Because chemotherapy resistance involves multip...

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Detalles Bibliográficos
Autores principales: Perez-Plasencia, Carlos, Duenas-Gonzalez, Alfonso
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540437/
https://www.ncbi.nlm.nih.gov/pubmed/16831224
http://dx.doi.org/10.1186/1476-4598-5-27