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Activation of the chicken Ig-β locus by the collaboration of scattered regulatory regions through changes in chromatin structure

A total of 10 B-lymphocyte-specific DNase I hypersensitive sites located in the chicken Ig-β locus were divided into four regions and combinations of deletions of these regions were carried out. A decrease in transcription of the Ig-β gene to <3% was demonstrated in cells with deletions in all fo...

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Detalles Bibliográficos
Autores principales: Shimada, Naoko, Matsudo, Hiroki, Osano, Kyoichi, Arakawa, Hiroshi, Buerstedde, Jean-Marie, Matsumoto, Yasuyuki, Chayahara, Kozue, Torihata, Atsushi, Ono, Masao
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540724/
https://www.ncbi.nlm.nih.gov/pubmed/16916790
http://dx.doi.org/10.1093/nar/gkl469