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High-throughput discovery of rare human nucleotide polymorphisms by Ecotilling
Human individuals differ from one another at only ∼0.1% of nucleotide positions, but these single nucleotide differences account for most heritable phenotypic variation. Large-scale efforts to discover and genotype human variation have been limited to common polymorphisms. However, these efforts ove...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540726/ https://www.ncbi.nlm.nih.gov/pubmed/16893952 http://dx.doi.org/10.1093/nar/gkl479 |