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Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repair

5-Hydroxyuracil is a major oxidized nucleobase that can be generated by the action of (•)OH radical and one-electron oxidants. The latter modified base that exhibits a low ionization potential is highly susceptible to further degradation upon exposure to various oxidants. Emphasis was placed in this...

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Detalles Bibliográficos
Autores principales: Simon, Philippe, Gasparutto, Didier, Gambarelli, Serge, Saint-Pierre, Christine, Favier, Alain, Cadet, Jean
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540730/
https://www.ncbi.nlm.nih.gov/pubmed/16885239
http://dx.doi.org/10.1093/nar/gkl496