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Formation of isodialuric acid lesion within DNA oligomers via one-electron oxidation of 5-hydroxyuracil: characterization, stability and excision repair
5-Hydroxyuracil is a major oxidized nucleobase that can be generated by the action of (•)OH radical and one-electron oxidants. The latter modified base that exhibits a low ionization potential is highly susceptible to further degradation upon exposure to various oxidants. Emphasis was placed in this...
Autores principales: | Simon, Philippe, Gasparutto, Didier, Gambarelli, Serge, Saint-Pierre, Christine, Favier, Alain, Cadet, Jean |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540730/ https://www.ncbi.nlm.nih.gov/pubmed/16885239 http://dx.doi.org/10.1093/nar/gkl496 |
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