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Real-time detection and continuous monitoring of ER stress in vitro and in vivo by ES-TRAP: evidence for systemic, transient ER stress during endotoxemia

Activity of secreted alkaline phosphatase (SEAP) produced by transfected cells is rapidly down-regulated by endoplasmic reticulum (ER) stress independent of transcriptional regulation. This phenomenon was observed in a wide range of cell types triggered by various ER stress inducers. The magnitude o...

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Detalles Bibliográficos
Autores principales: Hiramatsu, Nobuhiko, Kasai, Ayumi, Hayakawa, Kunihiro, Yao, Jian, Kitamura, Masanori
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540736/
https://www.ncbi.nlm.nih.gov/pubmed/16877567
http://dx.doi.org/10.1093/nar/gkl515