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Production of transmitochondrial cybrids containing naturally occurring pathogenic mtDNA variants
The human mitochondrial genome (mtDNA) encodes polypeptides that are critical for coupling oxidative phosphorylation. Our detailed understanding of the molecular processes that mediate mitochondrial gene expression and the structure–function relationships of the OXPHOS components could be greatly im...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540737/ https://www.ncbi.nlm.nih.gov/pubmed/16885236 http://dx.doi.org/10.1093/nar/gkl516 |