RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses

In recent years, tremendous insight has been gained on p53 regulation by targeting mutations at the p53 locus using homologous recombination in ES cells to generate mutant mice. Although informative, this approach is inefficient, slow and expensive. To facilitate targeting at the p53 locus, we devel...

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Detalles Bibliográficos
Autores principales: Toledo, Franck, Liu, Chung-Wen, Lee, Crystal J., Wahl, Geoffrey M.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540739/
https://www.ncbi.nlm.nih.gov/pubmed/16870721
http://dx.doi.org/10.1093/nar/gkl518

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540739/
https://www.ncbi.nlm.nih.gov/pubmed/16870721
http://dx.doi.org/10.1093/nar/gkl518

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