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RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses
In recent years, tremendous insight has been gained on p53 regulation by targeting mutations at the p53 locus using homologous recombination in ES cells to generate mutant mice. Although informative, this approach is inefficient, slow and expensive. To facilitate targeting at the p53 locus, we devel...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2006
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540739/ https://www.ncbi.nlm.nih.gov/pubmed/16870721 http://dx.doi.org/10.1093/nar/gkl518 |