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Specific and nontoxic silencing in mammalian cells with expressed long dsRNAs

A number of groups have developed libraries of siRNAs to identify genes through functional genomics. While these studies have validated the approach of making functional RNAi libraries to understand fundamental cellular mechanisms, they require information and knowledge of existing sequences since t...

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Detalles Bibliográficos
Autores principales: Strat, Aurel, Gao, Lu, Utsuki, Tada, Cheng, Bing, Nuthalapaty, Sam, Mathis, J. Mike, Odaka, Yoshinobu, Giordano, Tony
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1540741/
https://www.ncbi.nlm.nih.gov/pubmed/16916791
http://dx.doi.org/10.1093/nar/gkl532