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IfkA, a presumptive eIF2α kinase of Dictyostelium, is required for proper timing of aggregation and regulation of mound size

BACKGROUND: The transition from growth to development in Dictyostelium is initiated by amino acid starvation of growing amobae. In other eukaryotes, a key sensor of amino acid starvation and mediator of the resulting physiological responses is the GCN2 protein, an eIF2α kinase. GCN2 downregulates th...

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Detalles Bibliográficos
Autores principales: Fang, Rui, Xiong, Yanhua, Singleton, Charles K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154100/
https://www.ncbi.nlm.nih.gov/pubmed/12697064
http://dx.doi.org/10.1186/1471-213X-3-3