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Supervised versus unsupervised antimalarial treatment with six-dose artemether-lumefantrine: pharmacokinetic and dosage-related findings from a clinical trial in Uganda

BACKGROUND: A six-dose antimalarial regimen of artemether-lumefantrine (A/L) may soon become one of the most widely used drug combination in Africa, despite possible constraints with adherence and poor absorption due to inadequate nutrition, and a lack of pharmacokinetic and effectiveness data. METH...

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Detalles Bibliográficos
Autores principales: Checchi, Francesco, Piola, Patrice, Fogg, Carole, Bajunirwe, Francis, Biraro, Samuel, Grandesso, Francesco, Ruzagira, Eugene, Babigumira, Joseph, Kigozi, Isaac, Kiguli, James, Kyomuhendo, Juliet, Ferradini, Laurent, Taylor, Walter RJ, Guthmann, Jean-Paul
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543643/
https://www.ncbi.nlm.nih.gov/pubmed/16854236
http://dx.doi.org/10.1186/1475-2875-5-59