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Delayed minocycline inhibits ischemia-activated matrix metalloproteinases 2 and 9 after experimental stroke

BACKGROUND: Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are increased in the brain after experimental ischemic stroke in rats. These two proteases are involved with the degradation of the basal lamina and loss of stability of the blood brain barrier that occurs after ischemia and that is ass...

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Detalles Bibliográficos
Autores principales: Machado, Livia S, Kozak, Anna, Ergul, Adviye, Hess, David C, Borlongan, Cesario V, Fagan, Susan C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543649/
https://www.ncbi.nlm.nih.gov/pubmed/16846501
http://dx.doi.org/10.1186/1471-2202-7-56