Genetic context determines susceptibility to intraocular pressure elevation in a mouse pigmentary glaucoma

BACKGROUND: DBA/2J (D2) mice develop an age-related form of glaucoma. Their eyes progressively develop iris pigment dispersion and iris atrophy followed by increased intraocular pressure (IOP) and glaucomatous optic nerve damage. Mutant alleles of the Gpnmb and Tyrp1 genes are necessary for the iris...

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Detalles Bibliográficos
Autores principales: Anderson, Michael G, Libby, Richard T, Mao, Mao, Cosma, Ioan M, Wilson, Larry A, Smith, Richard S, John, Simon WM
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543659/
https://www.ncbi.nlm.nih.gov/pubmed/16827931
http://dx.doi.org/10.1186/1741-7007-4-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1543659/
https://www.ncbi.nlm.nih.gov/pubmed/16827931
http://dx.doi.org/10.1186/1741-7007-4-20

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