The relationship between predicted peptide–MHC class II affinity and T-cell activation in a HLA-DRβ1*0401 transgenic mouse model

The HLA-DRB1*0401 MHC class II molecule (DR4) is genetically associated with rheumatoid arthritis. It has been proposed that this MHC class II molecule participates in disease pathogenesis by presenting arthritogenic endogenous or exogenous peptides to CD4(+) T cells, leading to their activation and...

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Detalles Bibliográficos
Autores principales: Hill, Jonathan A, Wang, Dequn, Jevnikar, Anthony M, Cairns, Ewa, Bell, David A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154425/
https://www.ncbi.nlm.nih.gov/pubmed/12716452
http://dx.doi.org/10.1186/ar605

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154425/
https://www.ncbi.nlm.nih.gov/pubmed/12716452
http://dx.doi.org/10.1186/ar605

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