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Exposure to receptor-activator of NFκB ligand renders pre-osteoclasts resistant to IFN-γ by inducing terminal differentiation

While it has been established that IFN-γ is a strong activator of macrophages and a potent inhibitor of osteoclastogenesis in vitro, it is also known that this cytokine is produced in particular settings of inflammatory bone loss, such as infection and psoriatic arthritis. Because of the different k...

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Detalles Bibliográficos
Autores principales: Huang, Willis, O'Keefe, Regis J, Schwarz, Edward M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154432/
https://www.ncbi.nlm.nih.gov/pubmed/12716453
http://dx.doi.org/10.1186/ar612