Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes

Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that the development of autoimmune lesions...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeinstra, Esther, Wilczak, Nadine, Chesik, Daniel, Glazenburg, Lisa, Kroese, Frans GM, De Keyser, Jacques
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544322/
https://www.ncbi.nlm.nih.gov/pubmed/16859542
http://dx.doi.org/10.1186/1742-2094-3-16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544322/
https://www.ncbi.nlm.nih.gov/pubmed/16859542
http://dx.doi.org/10.1186/1742-2094-3-16

Ejemplares similares