Simvastatin inhibits interferon-γ-induced MHC class II up-regulation in cultured astrocytes
Based on their potent anti-inflammatory properties and a preliminary clinical trial, statins (HMG-CoA reductase inhibitors) are being studied as possible candidates for multiple sclerosis (MS) therapy. The pathogenesis of MS is unclear. One theory suggests that the development of autoimmune lesions...
Autores principales: | , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544322/ https://www.ncbi.nlm.nih.gov/pubmed/16859542 http://dx.doi.org/10.1186/1742-2094-3-16 |