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Transient change in GABA(A )receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration

BACKGROUND: Lurcher mice suffer from a complete Purkinje cell (PC) loss in the first four postnatal weeks. Parallel to this degeneration, GABAergic synapses in the deep cerebellar nuclei (DCN), the major recipient of the inhibitory PC projection, increase synaptic conductance. Here, we further inves...

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Detalles Bibliográficos
Autores principales: Linnemann, C, Schmeh, I, Thier, P, Schwarz, C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1544347/
https://www.ncbi.nlm.nih.gov/pubmed/16872511
http://dx.doi.org/10.1186/1471-2202-7-59