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Haplotypic analysis of the TNF locus by association efficiency and entropy

BACKGROUND: To understand the causal basis of TNF associations with disease, it is necessary to understand the haplotypic structure of this locus. We genotyped 12 single-nucleotide polymorphisms (SNPs) distributed over 4.3 kilobases in 296 healthy, unrelated Gambian and Malawian adults. We generated...

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Detalles Bibliográficos
Autores principales: Ackerman, Hans, Usen, Stanley, Mott, Richard, Richardson, Anna, Sisay-Joof, Fatoumatta, Katundu, Pauline, Taylor, Terrie, Ward, Ryk, Molyneux, Malcolm, Pinder, Margaret, Kwiatkowski, Dominic P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC154575/
https://www.ncbi.nlm.nih.gov/pubmed/12702205
http://dx.doi.org/10.1186/gb-2003-4-4-r24