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Low NO bioavailability in CCl(4 )cirrhotic rat livers might result from low NO synthesis combined with decreased superoxide dismutase activity allowing superoxide-mediated NO breakdown: A comparison of two portal hypertensive rat models with healthy controls

BACKGROUND: In cirrhotic livers, the balance of vasoactive substances is in favour of vasoconstrictors with relatively insufficient nitric oxide. Endothelial dysfunction has been documented in cirrhotic rat livers leading to a lower activity of endothelial nitric oxide synthase but this might not be...

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Detalles Bibliográficos
Autores principales: Van de Casteele, Marc, van Pelt, Jos F, Nevens, Frederik, Fevery, Johan, Reichen, Jürg
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155038/
https://www.ncbi.nlm.nih.gov/pubmed/12575897
http://dx.doi.org/10.1186/1476-5926-2-2