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Molecular profiling of signalling proteins for effects induced by the anti-cancer compound GSAO with 400 antibodies

BACKGROUND: GSAO (4-[N-[S-glutathionylacetyl]amino] phenylarsenoxide) is a hydrophilic derivative of the protein tyrosine phosphatase inhibitor phenylarsine oxide (PAO). It inhibits angiogenesis and tumour growth in mouse models and may be evaluated in a phase I clinical trial in the near future. In...

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Detalles Bibliográficos
Autores principales: Cadd, Verity A, Hogg, Philip J, Harris, Adrian L, Feller, Stephan M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550423/
https://www.ncbi.nlm.nih.gov/pubmed/16764713
http://dx.doi.org/10.1186/1471-2407-6-155