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Activated protein C increases sensitivity to vasoconstriction in rabbit Escherichia coli endotoxin-induced shock

INTRODUCTION: The aim of this study was to investigate the effects of activated protein C (aPC) on vascular function, endothelial injury, and haemostasis in a rabbit endotoxin-induced shock model. METHOD: This study included 22 male New Zealand rabbits weighing 2.5 to 3 kg each. In vitro vascular re...

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Detalles Bibliográficos
Autores principales: Wiel, Eric, Costecalde, Marion Elizabeth, Lebuffe, Gilles, Corseaux, Delphine, Jude, Brigitte, Bordet, Régis, Tavernier, Benoît, Vallet, Benoît
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550919/
https://www.ncbi.nlm.nih.gov/pubmed/16542507
http://dx.doi.org/10.1186/cc4858