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Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome

INTRODUCTION: Protein C, because of its central role in hemostasis, plays an integral role in the host response to infection. Protein C depletion, resulting from increased consumption, degradation, and/or decreased synthesis, is characteristic of sepsis and has been shown to predict morbidity and mo...

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Detalles Bibliográficos
Autores principales: Shorr, Andrew F, Bernard, Gordon R, Dhainaut, Jean-Francois, Russell, James R, Macias, William L, Nelson, David R, Sundin, David P
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550956/
https://www.ncbi.nlm.nih.gov/pubmed/16780598
http://dx.doi.org/10.1186/cc4946