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Rho-kinase regulates tissue morphogenesis via non-muscle myosin and LIM-kinase during Drosophila development

BACKGROUND: The Rho-kinases (ROCKs) are major effector targets of the activated Rho GTPase that have been implicated in many of the Rho-mediated effects on cell shape and movement via their ability to affect acto-myosin contractility. The role of ROCKs in cell shape change and motility suggests a po...

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Detalles Bibliográficos
Autores principales: Verdier, Valerie, Guang-Chao-Chen, Settleman, Jeffrey
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1552057/
https://www.ncbi.nlm.nih.gov/pubmed/16882341
http://dx.doi.org/10.1186/1471-213X-6-38