Genetic heterogeneity in response to adenovirus gene therapy

BACKGROUND: After intravenous delivery of the adenoviral vector into rats or mice, 95–99% of the encoded protein is produced in the hepatocytes. We observed, as have others, that the early expression levels of the vector encoded protein vary, greatly, within a species, from one animal strain to anot...

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Detalles Bibliográficos
Autores principales: Lefesvre, Pierre, Attema, Joline, Lemckert, Angelique, Havenga, Menzo, Bekkum, Dirk van
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2003
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155537/
https://www.ncbi.nlm.nih.gov/pubmed/12697054
http://dx.doi.org/10.1186/1471-2199-4-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC155537/
https://www.ncbi.nlm.nih.gov/pubmed/12697054
http://dx.doi.org/10.1186/1471-2199-4-4

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