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Comparative genomics of the class 4 histone deacetylase family indicates a complex evolutionary history

BACKGROUND: Histone deacetylases are enzymes that modify core histones and play key roles in transcriptional regulation, chromatin assembly, DNA repair, and recombination in eukaryotes. Three types of related histone deacetylases (classes 1, 2, and 4) are widely found in eukaryotes, and structurally...

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Detalles Bibliográficos
Autores principales: Ledent, Valérie, Vervoort, Michel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1555614/
https://www.ncbi.nlm.nih.gov/pubmed/16884538
http://dx.doi.org/10.1186/1741-7007-4-24