Efficient generation of double heterologous promoter controlled oncolytic adenovirus vectors by a single homologous recombination step in Escherichia coli

BACKGROUND: Oncolytic adenoviruses are promising agents for the multimodal treatment of cancer. However, tumor-selectivity is crucial for their applicability in patients. Recent studies by several groups demonstrated that oncolytic adenoviruses with tumor-/tissue-specific expression of the E1 and E4...

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Detalles Bibliográficos
Autores principales: Hoffmann, Dennis, Wildner, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557486/
https://www.ncbi.nlm.nih.gov/pubmed/16887042
http://dx.doi.org/10.1186/1472-6750-6-36

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557486/
https://www.ncbi.nlm.nih.gov/pubmed/16887042
http://dx.doi.org/10.1186/1472-6750-6-36

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