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Cysteinyl-leukotrienes in the regulation of β(2)-adrenoceptor function: an in vitro model of asthma

BACKGROUND: The response to β(2)-adrenoceptor agonists is reduced in asthmatic airways. This desensitization may be in part due to inflammatory mediators and may involve cysteinyl-leukotrienes (cysteinyl-LTs). Cysteinyl-LTs are pivotal inflammatory mediators that play important roles in the pathophy...

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Detalles Bibliográficos
Autores principales: Rovati, G Enrico, Baroffio, Michele, Citro, Simona, Brichetto, Lorenzo, Ravasi, Saula, Milanese, Manlio, Crimi, Emanuele, Brusasco, Vito
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557489/
https://www.ncbi.nlm.nih.gov/pubmed/16875498
http://dx.doi.org/10.1186/1465-9921-7-103