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The μ-opioid receptor gene and smoking initiation and nicotine dependence
The gene encoding the mu-opioid receptor (OPRM1) is reported to be associated with a range of substance dependence. Experiments in knockout mice indicate that the mu-opioid receptor may mediate reinforcing effects of nicotine. In humans, opioid antagonist naltrexone may reduce the reinforcing effect...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2006
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557520/ https://www.ncbi.nlm.nih.gov/pubmed/16887046 http://dx.doi.org/10.1186/1744-9081-2-28 |