Sequence-dependent enhancement of hydrolytic deamination of cytosines in DNA by the restriction enzyme PspGI

Hydrolytic deamination of cytosines in DNA creates uracil and, if unrepaired, these lesions result in C to T mutations. We have suggested previously that a possible way in which cells may prevent or reduce this chemical reaction is through the binding of proteins to DNA. We use a genetic reversion a...

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Detalles Bibliográficos
Autores principales: Carpenter, Michael, Divvela, Pradeep, Pingoud, Vera, Bujnicki, Janusz, Bhagwat, Ashok S.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557792/
https://www.ncbi.nlm.nih.gov/pubmed/16893959
http://dx.doi.org/10.1093/nar/gkl545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557792/
https://www.ncbi.nlm.nih.gov/pubmed/16893959
http://dx.doi.org/10.1093/nar/gkl545

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