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Complexed crystal structure of replication restart primosome protein PriB reveals a novel single-stranded DNA-binding mode

PriB is a primosomal protein required for replication restart in Escherichia coli. PriB stimulates PriA helicase activity via interaction with single-stranded DNA (ssDNA), but the molecular details of this interaction remain unclear. Here, we report the crystal structure of PriB complexed with a 15...

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Detalles Bibliográficos
Autores principales: Huang, Cheng-Yang, Hsu, Che-Hsiung, Sun, Yuh-Ju, Wu, Huey-Nan, Hsiao, Chwan-Deng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557812/
https://www.ncbi.nlm.nih.gov/pubmed/16899446
http://dx.doi.org/10.1093/nar/gkl536