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Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors

BACKGROUND: Estrogen plays a central role in breast cancer pathogenesis. Although many studies have characterized the estrogen regulation of genes using in vitro cell culture models by global mRNA expression profiling, it is not clear whether these genes are similarly regulated in vivo or how they m...

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Detalles Bibliográficos
Autores principales: Creighton, Chad J, Cordero, Kevin E, Larios, Jose M, Miller, Rebecca S, Johnson, Michael D, Chinnaiyan, Arul M, Lippman, Marc E, Rae, James M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557996/
https://www.ncbi.nlm.nih.gov/pubmed/16606439
http://dx.doi.org/10.1186/gb-2006-7-4-r28