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Benchmarking ortholog identification methods using functional genomics data

BACKGROUND: The transfer of functional annotations from model organism proteins to human proteins is one of the main applications of comparative genomics. Various methods are used to analyze cross-species orthologous relationships according to an operational definition of orthology. Often the defini...

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Detalles Bibliográficos
Autores principales: Hulsen, Tim, Huynen, Martijn A, de Vlieg, Jacob, Groenen, Peter MA
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1557999/
https://www.ncbi.nlm.nih.gov/pubmed/16613613
http://dx.doi.org/10.1186/gb-2006-7-4-r31