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The cyclin D1b splice variant: an old oncogene learns new tricks
The function of cyclin D1 as a positive regulator of the cell cycle and proto-oncogene has been well established. Cyclin D1 elicits its pro-proliferative function early in G1 phase, through its ability to activate cyclin dependent kinase (CDK) 4 or 6. Active CDK4/6-cyclin D1 complexes phosphorylate...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2006
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559605/ https://www.ncbi.nlm.nih.gov/pubmed/16863592 http://dx.doi.org/10.1186/1747-1028-1-15 |