Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes

Cytotoxic T lymphocytes (CTL) protect against viruses including HIV-1. To avoid viral escape mutants that thwart immunity, we chose 25 CTL epitopes defined in the context of natural infection with functional and/or structural constraints that maintain sequence conservation. By combining HLA binding...

Descripción completa

Detalles Bibliográficos
Autores principales: Reche, Pedro A, Keskin, Derin B, Hussey, Rebecca E, Ancuta, Petronela, Gabuzda, Dana, Reinherz, Ellis L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559620/
https://www.ncbi.nlm.nih.gov/pubmed/16674822
http://dx.doi.org/10.1186/1476-9433-5-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559620/
https://www.ncbi.nlm.nih.gov/pubmed/16674822
http://dx.doi.org/10.1186/1476-9433-5-1

Ejemplares similares