Cargando…

Elicitation from virus-naive individuals of cytotoxic T lymphocytes directed against conserved HIV-1 epitopes

Cytotoxic T lymphocytes (CTL) protect against viruses including HIV-1. To avoid viral escape mutants that thwart immunity, we chose 25 CTL epitopes defined in the context of natural infection with functional and/or structural constraints that maintain sequence conservation. By combining HLA binding...

Descripción completa

Detalles Bibliográficos
Autores principales:	Reche, Pedro A, Keskin, Derin B, Hussey, Rebecca E, Ancuta, Petronela, Gabuzda, Dana, Reinherz, Ellis L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2006
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559620/ https://www.ncbi.nlm.nih.gov/pubmed/16674822 http://dx.doi.org/10.1186/1476-9433-5-1

Ejemplares similares

Conservation Analysis of Dengue Virus T-cell Epitope-Based Vaccine Candidates Using Peptide Block Entropy
por: Olsen, Lars Rønn, et al.
Publicado: (2011)

PVS: a web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery
por: Garcia-Boronat, Maria, et al.
Publicado: (2008)

PEPVAC: a web server for multi-epitope vaccine development based on the prediction of supertypic MHC ligands
por: Reche, Pedro A., et al.
Publicado: (2005)

Serological Markers for Inflammatory Bowel Disease in AIDS Patients with Evidence of Microbial Translocation
por: Kamat, Anupa, et al.
Publicado: (2010)

Characterization of Conserved and Promiscuous Human Rhinovirus CD4 T Cell Epitopes
por: Gomez-Perosanz, Marta, et al.
Publicado: (2021)

Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals
por: Blanco-Heredia, Juan, et al.
Publicado: (2016)

Molecular Detection of Targeted Major Histocompatibility Complex I-Bound Peptides Using a Probabilistic Measure and Nanospray MS(3) on a Hybrid Quadrupole-Linear Ion Trap
por: Reinhold, Bruce, et al.
Publicado: (2010)

Forward Vaccinology: CTL Targeting Based upon Physical Detection of HLA-Bound Peptides
por: Reinherz, Ellis L., et al.
Publicado: (2014)

Correction: Identification of Immunogenic Cytotoxic T Lymphocyte Epitopes Containing Drug Resistance Mutations in Antiretroviral Treatment-Naïve HIV-Infected Individuals
por: Blanco-Heredia, Juan, et al.
Publicado: (2016)

Design of Cytotoxic T Cell Epitopes by Machine Learning of Human Degrons
por: Truex, Nicholas L., et al.
Publicado: (2023)

Fractalkine Preferentially Mediates Arrest and Migration of CD16(+) Monocytes
por: Ancuta, Petronela, et al.
Publicado: (2003)

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets
por: Ancuta, Petronela, et al.
Publicado: (2009)

A Plasma Biomarker Signature of Immune Activation in HIV Patients on Antiretroviral Therapy
por: Kamat, Anupa, et al.
Publicado: (2012)

Engineered immunogens to elicit antibodies against conserved coronavirus epitopes
por: Kapingidza, A. Brenda, et al.
Publicado: (2023)

A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes
por: Sun, Lu, et al.
Publicado: (2014)

HLA-A2-Restricted Epitopes Identified from MTA1 Could Elicit Antigen-Specific Cytotoxic T Lymphocyte Response
por: Wu, Yahong, et al.
Publicado: (2018)

PB1-F2 Finder: scanning influenza sequences for PB1-F2 encoding RNA segments
por: DeLuca, David S, et al.
Publicado: (2011)

Effective Suppression of HIV-1 Replication by Cytotoxic T Lymphocytes Specific for Pol Epitopes in Conserved Mosaic Vaccine Immunogens
por: Zou, Chengcheng, et al.
Publicado: (2019)

Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers
por: Fathi, Mohsen, et al.
Publicado: (2022)

Selection of Conserved Epitopes from Hepatitis C Virus for Pan-Populational Stimulation of T-Cell Responses
por: Molero-Abraham, Magdalena, et al.
Publicado: (2013)

TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
por: Zhang, Guanglan, et al.
Publicado: (2021)

High frequency of cross-reactive cytotoxic T lymphocytes elicited during the virus-induced polyclonal cytotoxic T lymphocyte response
Publicado: (1993)

Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction
por: Larsen, Mette V, et al.
Publicado: (2007)

Identification of two cytotoxic T lymphocyte-recognized epitopes in the Ras protein
Publicado: (1993)

HPVdb: a data mining system for knowledge discovery in human papillomavirus with applications in T cell immunology and vaccinology
por: Zhang, Guang Lan, et al.
Publicado: (2014)

Identification of Cytotoxic T Lymphocyte Epitopes on Swine Viruses: Multi-Epitope Design for Universal T Cell Vaccine
por: Liao, Yu-Chieh, et al.
Publicado: (2013)

Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
por: Fan, Chengcheng, et al.
Publicado: (2022)

Human rhinovirus‐specific CD8 T cell responses target conserved and unusual epitopes
por: Gomez‐Perosanz, Marta, et al.
Publicado: (2020)

Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes
por: Ip, Peng Peng, et al.
Publicado: (2015)

Prediction and identification of mouse cytotoxic T lymphocyte epitopes in Ebola virus glycoproteins
por: Wu, Shipo, et al.
Publicado: (2012)

West Nile Virus Vaccine Design by T Cell Epitope Selection: In Silico Analysis of Conservation, Functional Cross-Reactivity with the Human Genome, and Population Coverage
por: Waller, Frances M., et al.
Publicado: (2020)

Different responses are elicited in cytotoxic T lymphocytes by different levels of T cell receptor occupancy
Publicado: (1996)

Antitumor activity of antibody against cytotoxic T lymphocyte epitope peptide of lymphocyte‐specific protein tyrosine kinase
por: Matsueda, Satoko, et al.
Publicado: (2018)

A Strategy for Eliciting Antibodies against Cryptic, Conserved, Conformationally Dependent Epitopes of HIV Envelope Glycoprotein
por: Kelker, Hanna C., et al.
Publicado: (2010)

Designed nanoparticles elicit cross-reactive antibody responses to conserved influenza virus hemagglutinin stem epitopes
por: McCraw, Dustin M., et al.
Publicado: (2023)

Comparison of the depth of vaccine-elicited HIV-1 Env epitope-specific CD8+ T lymphocyte responses
por: Hulot, SL, et al.
Publicado: (2012)

MULTIPRED2: A computational system for large-scale identification of peptides predicted to bind to HLA supertypes and alleles
por: Zhang, Guang Lan, et al.
Publicado: (2011)

New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination
por: Fridkis-Hareli, Masha, et al.
Publicado: (2004)

Fundamentals and Methods for T- and B-Cell Epitope Prediction
por: Sanchez-Trincado, Jose L., et al.
Publicado: (2017)

An immunodominant epitope present in multiple class I MHC molecules and recognized by cytotoxic T lymphocytes
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_2p9j4qvoloda3oei50qd3oi267