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Inferring direct regulatory targets from expression and genome location analyses: a comparison of transcription factor deletion and overexpression

BACKGROUND: Effects on gene expression due to environmental or genetic changes can be easily measured using microarrays. However, indirect effects on expression can be substantial. The indirect effects of a perturbation need to be distinguished from the direct effects if we are to understand the str...

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Detalles Bibliográficos
Autores principales: Tang, Lin, Liu, Xiao, Clarke, Neil D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1559704/
https://www.ncbi.nlm.nih.gov/pubmed/16923194
http://dx.doi.org/10.1186/1471-2164-7-215